CATECHOL: IMPORTANT SCAFOLD IN MEDICINAL CHEMISTRY

Khemchand R. Surana; Aarti J. Ahire; Sagar V. Bhawar; Prachi D. Jeughale; Kalyani J. Aher; Chetana G. Ahire; Akshad D. Bagul; Mayur V. Chavan; Dhananjay M. Patil; Deepak D. Sonawane

Authors

Khemchand R. Surana Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0000-0001-8918-1159
Aarti J. Ahire Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0003-3577-4532
Sagar V. Bhawar Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0000-5888-2681
Prachi D. Jeughale Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0005-0172-9068
Kalyani J. Aher Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0008-4548-5255
Chetana G. Ahire Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0008-9562-7098
Akshad D. Bagul Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0008-0834-5923
Mayur V. Chavan Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0007-5915-4978
Dhananjay M. Patil Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0005-7555-132X
Deepak D. Sonawane Department of Pharmaceutics, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, Maharashtra, India. https://orcid.org/0009-0004-1908-5750

Keywords:

Catechol, Synthetic methods of coumarin, Anticancer, Antioxidant, Anti-inflammatory, Biological activity.

Abstract

The catechol scaffold is a significant structural component in medicinal chemistry since it is present in many naturally occurring compounds with varied biological effects, such as those that are anti-cancer, anti-inflammatory, antioxidant, anti-diabetic, antimicrobial, antiviral, and antifungal. Additionally, several other synthetic catechol motifs can be found in marketed drugs. They also play a part in a variety of physiological procedures and infection defence. This review will provide an overview of catechol moieties with medical applications synthesised in the previous 15 years by choosing the most effective compound from each publication. In this review, many methods for producing catechol and its derivatives have been discussed.

CATECHOL: IMPORTANT SCAFOLD IN MEDICINAL CHEMISTRY

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