UTILIZATION OF ULTRABRIGHT NANOCARRIERS IN BIOIMAGING TECHNIQUE

Abstract

The review article focuses on development and pharmaceutical applications of ultrabright nanocarriers in advanced drug delivery due to their biocompatibility, size, target-specificity and increased efficacy properties. These include dendrimers, polymeric micelles, solid-lipid nanoparticles, C dots, integrins etc. Their objective is safe and effective delivery of highly hydrophobic drugs, improving their pharmacokinetics as well as bio-distribution potential, thus minimizing their potential toxicity. Various researchers have emphasized on the assembling organic molecules into biodegradable nanoparticles featuring much higher brightness than single dye molecules. Modifications in nanoparticles have been implemented to change the color in response to single biomolecule such as proteins and nucleic acids. Nanoparticle technology has been as an analytical tool in both cancer cell research and medical diagnostics.